What is organomegaly?

Organomegaly involves the enlargement of the body's organs. Many different factors can cause such enlargement. While some causes are benign, others are more serious. Heart enlargement, liver enlargement, and spleen enlargement, called cardiomegaly, hepatomegaly, and splenomegaly, respectively, represent three examples of abnormal organ enlargement. Autoimmune disorders often cause organomegaly as well.

Organomegaly most often manifests as a symptom of a disorder, rather than being the disorder itself. Hepatomegaly, for example, can be the result of a number of diverse medical problems, ranging from infection to tumors. Congestive heart failure frequently facilitates cardiomegaly. Organ enlargement usually coincides with other symptoms related to a particular disorder. With various liver dysfunctions, jaundice or yellowish skin often occurs together with organomegaly.

Enlargement of large organs is commonly detectable by the presence of a mass. In hepatomegaly, an abdominal mass may form. Cardiomegaly can cause swelling in the chest area, specifically if the heart is at least 50 percent larger than the inside of the rib cage. Ultrasounds, blood tests, and physical exams can also help locate organomegaly and offer some insight into possible causes.

One of the most common forms of organomegaly is an enlarged spleen. This organ is located in the upper abdomen, and its enlargement usually results from stress on the body due to hypertension. Any stressful bodily influence like high blood pressure or cancer can enlarge the spleen to dangerous levels. Pain in the chest, abdomen, and back are the most common effects. Splenomegaly usually requires surgical removal of the spleen.

Both splenomegaly and hepatomegaly are found in autoimmune diseases. Although these disorders are rare, organomegaly is a primary feature. When the body's immune system attacks the endocrine organs, such as the various glands in the body, conditions such as autoimmune polyendocrine syndrome and POEMS (an acronym derived from the main disorders of the syndrome: polyneurothapy, organomegaly, endocrinopathy, monoclonal gammopathy, and polyendocrine changes) occur. on the skin). Susceptibility to frequent infections is a consequence of the conditions, as is the numbness and weakness of the limbs in the case of POEMS syndrome. Paraproteins located in the urine and blood contribute to the abnormalities.

Although exercise and other harmless factors can lead to enlargement of the body's organs, chronic organomegaly should never be taken lightly. As stated, many serious and potentially life-threatening conditions may be responsible. In the case of POEMS syndrome, some research claims that the survival rate is less than half at five years after onset if the disorder is not treated. Since organ enlargement usually has an underlying cause, discovery and treatment of the underlying disorder is crucial. A trained medical professional can best evaluate all options and outcomes.

Go up