What are the causes of eosinophilia?

One of the most common causes of eosinophilia is an allergic reaction or illness related to an over-response of the immune system. An infection from a parasite such as roundworm and hookworm can also cause the condition. Eosinophilia can also be caused by some cancers, autoimmune diseases, or lung diseases. The signs of eosinophilia are variable and depend on the conditions causing this medical problem. Treatment of eosinophilia begins with identifying the cause of the condition and then using oral, topical, or inhaled corticosteroids.

Eosinophils are white blood cells that destroy foreign particles and advance the inflammation process that limits an infection. The medical condition of eosinophilia occurs when there is a prolonged elevation in the normal number of eosinophils in the body. An allergic reaction initiates an inflammatory response to immobilize and contain the foreign substances, resulting in a rush of eosinophils to the irritated site. As a result, a prolonged allergic reaction to environmental stimuli, medications, or food is one of the most common causes of eosinophilia. For the same reason, an isolating inflammatory response or an immune reaction to a parasitic or fungal infection are other common causes of eosinophilia.

Other medial problems can cause eosinophilia for two reasons. First, diseases such as cancer can overstimulate the bone marrow to generate excess eosinophils. Second, these conditions can cause high concentrations of eosinophils to concentrate at tumor sites or damaged tissue.

The signs of eosinophilia vary greatly depending on the cause of this condition. Fungal and parasitic infections that cause eosinophilia can cause abdominal discomfort, diarrhea, and mouth sores. Eosinophilia caused by fungal or parasitic invasions can even lead to pneumonia. In rare cases, symptoms can include enlarged lymph nodes, weight loss, and skin rashes.

Treatment of eosinophilia involves first identifying the cause of the condition. This will be done by reviewing the patient's medical history and monitoring their diet and medications to find a possible allergen. Skin tests may be ordered to confirm a suspected allergy. Potential fungal and parasitic infections will be identified by analyzing the patient's recent travels and potential exposure.

Once the cause of eosinophilia is identified, the medical condition will be treated. In addition, the patient can receive corticosteroid therapy in a manner that best suits the patient and the cause. Corticosteroids can be prescribed orally, inhaled or topically. Most eosinophilia can be corrected over time.

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